stage.napdi.org

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-YlzfNg Goldenseal (Hydrastis canadensis) R21 Goldenseal Project Intravenous Metformin/Oral Inhibitor Mouse Study - Imatinib In Vivo Interaction negative — No Effect (based on bioequivalence limits)
metformin imatinib
NPDI-yewsDg Goldenseal (Hydrastis canadensis) R21 Goldenseal Project Oral Metformin/Oral Inhibitor Mouse Study - Imatinib In Vivo Interaction positive — PK Interaction - Decreased systemic exposure
metformin imatinib

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