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  • Cat's-claw (Uncaria tomentosa)

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-TVYo2w Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/500 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
cat's claw extract
NPDI-A3--xw Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/1000 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
cat's claw extract
NPDI-CL8itw Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
cat's claw extract
NPDI-Hr_w8g Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/2500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
cat's claw extract
NPDI-7n3MdQ Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/7500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
cat's claw extract
NPDI-SRsArQ Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/100 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
cat's claw extract
NPDI-DbntYQ Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/1000 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
cat's claw extract
NPDI-VOj3Ug Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/2500 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
cat's claw extract
NPDI-h8CxDA Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/1000 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam cat's claw extract
NPDI-1G7o6Q Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/5000 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
cat's claw extract
NPDI-nRt2ng Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/500 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam cat's claw extract
NPDI-UbcSjQ Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/5000 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
cat's claw extract
NPDI-hg991g Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/5000 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam cat's claw extract
NPDI-NxBuuA Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Cat's Claw 1/2500 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam cat's claw extract