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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-2MTmoQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/1000 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-cyF5-w Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/500 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-lVB-wQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/250 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-jQcPOw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/50 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-yLL5dw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/2500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction negative — In Vitro Nuclear Receptor Non-induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-FsyoWg Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/2500 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-sfIKSQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/50 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-TIcCbg Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/250 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-oFo-ZQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/100 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-jhBFQw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/500 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-boTo-Q Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-Jo6i8g Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/100 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-irr70Q Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/100 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-mNNsbA Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/5000 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction negative — In Vitro Nuclear Receptor Non-induction
  • CYP3A4
gou teng extract
NPDI-vUVs_g Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/2500 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract