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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-l6H7hA Shrubby sophora (Sophora flavescens) Chinese Herbal Medicine Sophora Flavescens Activates PXR Sophora Flavescens - Effect on PXR Activation in DPX2 Cells Experiment - 1 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
sophora flavescens
NPDI-2Jtpug Shrubby sophora (Sophora flavescens) Chinese Herbal Medicine Sophora Flavescens Activates PXR Sophora Flavescens - Effect of Sophora Flavescens 0.5 g/L and N-Methylcytisine on CYP3A4 in DPX2 Cells Experiment - 4 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
sophora flavescens
NPDI-COzHAQ Shrubby sophora (Sophora flavescens) Chinese Herbal Medicine Sophora Flavescens Activates PXR Sophora Flavescens - Effect of Sophora Flavescens 0.5 g/L and N-Methylcytisine on CYP3A4 in HepaRG Cells Experiment - 2 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
sophora flavescens
NPDI-3jqrbg Shrubby sophora (Sophora flavescens) Chinese Herbal Medicine Sophora Flavescens Activates PXR Sophora Flavescens - Effect of Sophora Flavescens 5 g/L and N-Methylcytisine on CYP3A4 in DPX2 Cells Experiment - 2 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
sophora flavescens
NPDI-WjNEBg Shrubby sophora (Sophora flavescens) Chinese Herbal Medicine Sophora Flavescens Activates PXR Sophora Flavescens - Pretreatment of Sophora Flavescens and Constituents on CYP3A4 in DPX2 Cells Experiment - 6 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
sophora flavescens
NPDI-DJBgHg Shrubby sophora (Sophora flavescens) Chinese Herbal Medicine Sophora Flavescens Activates PXR Sophora Flavescens - Effect of Sophora Flavescens 1 g/L and N-Methylcytisine on CYP3A4 in DPX2 Cells Experiment - 3 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
sophora flavescens