- Natural product: Green tea (Camellia sinensis)
- Associated study: Green tea ingestion greatly reduces plasma concentrations of nadolol in healthy subjects.
In Vitro Transporter Inhibition Experiment
OATP1A2 in vitro inhibition
Inhibition was detected. Cutoff used — not clearly specified
nadolol 1313200
- OATP1A2 (SLCO1A2)
Transfected / siRNA knock-out / injected cells HEK293 transfected cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
poly-D-lysine hydrobromide-coated 12-well plates
2
5 min
37 deg C
7.3
100 µM
1, 10, 100, and 1000 µM
not specified