- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450
In Vitro Enzyme Inhibition Experiment
Inhibition was detected. Cutoff used — N/A
- CYP1A1 4173297
Recombinant expression system Not available
Cytochrome B5 Not available
Results
The apparent Ki value is presented in the table.
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.
CYP: 20 pmol/mL
In-house preparation
0.5 mL
15 min
NADPH regenerating system
Not available
Not available
10 µM
50 µM