Plasma Concentrations of Secobarbital After Placebo Pretreatment and Oral Administration of Secobarbital CSV JSON
- Natural product: Cannabis (Cannabis sativa)
- Associated study: Influence of cannabidiol on secobarbital effects and plasma kinetics
In Vivo Interaction Study
Plasma Concentrations of Secobarbital After Placebo Pretreatment and Oral Administration of Secobarbital
No Effect (based on bioequivalence limits) was detected.
Table 1.
Results
Values converted from µg/mL.
Original value: Cmax (µg/mL): 2.59 ± 0.94
Table 1.
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
Double-blind
Placebo-controlled
Single dosing
Healthy volunteers
Males
6
"No subjects used drugs or medication habitually, but all had previously smoked marijuana. Subjects were instructed to fast at least four hours prior to the experimental session and to eat a light breakfast consisting of dry toast and juice. [...] All sessions were separated by at least one week."
0, 15, 30, 45, 60, 75, 90, 105, 120, 150, 180, 210, 240, 270, 300 min, 24, 48, and 72 h
Drug or Natural Product Administration
Oral
Capsule
150 mg/70 kg
Once
Inhalation
Cigarette
0 mg
Once
Not specified