- Natural product: Cannabis (Cannabis sativa)
- Associated study: Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety.
In Vitro Enzyme Inhibition Experiment
Cannabidiol
Inhibition was detected. Cutoff used — Not specified
- CYP1A1 4173297
Recombinant expression system Baculovirus-insect cells
Cytochrome B5 No
Results
Estimated from Fig 4a. CBD 1 μM.
Table 1
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
Commercially available
200 μL
NADPH
5 min