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(-)-beta-hydrastine

Need public description.

Compound information managed by NaPDI

  • Goldenseal (Hydrastis canadensis)

hydrastine

None listed

None listed

None listed
ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-yehRxQ Goldenseal (Hydrastis canadensis) R21 Goldenseal Project Oral Metformin/Oral Inhibitor Mouse Study - (-)-β-hydrastine In Vivo Interaction negative — No Effect (based on bioequivalence limits)
metformin (-)-beta-hydrastine
NPDI-wdarow Goldenseal (Hydrastis canadensis) Human Cytochrome P450 Inhibition and Metabolic-Intermediate Complex Formation By Goldenseal Extract and Its Methylenedioxyphenyl Components 2C9 Inhibition by (-) Hydrastine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C9
diclofenac 4'-hydroxydiclofenac (-)-beta-hydrastine
NPDI-CDvKlQ Goldenseal (Hydrastis canadensis) Human Cytochrome P450 Inhibition and Metabolic-Intermediate Complex Formation By Goldenseal Extract and Its Methylenedioxyphenyl Components 3A4 Inhibition by (-) Hydrastine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
testosterone 6beta-hydroxytestosterone (-)-beta-hydrastine
NPDI-UaWFPQ Goldenseal (Hydrastis canadensis) Human Cytochrome P450 Inhibition and Metabolic-Intermediate Complex Formation By Goldenseal Extract and Its Methylenedioxyphenyl Components 2D6 Inhibition by (-) Hydrastine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2D6
bufuralol 1'-hydroxybufuralol (-)-beta-hydrastine
NPDI-9t7UTw Goldenseal (Hydrastis canadensis) Goldenseal Characterization of Material Goldenseal Characterization of Material Experiment Characterization of Material