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nicardipine
InChIKey: ZBBHBTPTTSWHBA-UHFFFAOYSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI--hYNlQ Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by Nicardipine (Positive Control; Screening) In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 4'-glucuronide nicardipine
NPDI-N39uaQ Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT by Nicardipine in HIM (Screening) In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • UGT
4-methylumbelliferone 4-methylumbelliferone glucuronide nicardipine
NPDI-yWS4NQ Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1 and 1A8 by Nicardipine (Positive Control; Screening) In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A8
raloxifene raloxifene 6-glucuronide nicardipine

Compound information from external resources

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