NaPDI | Compound details

stage.napdi.org

Need public description.

Natural products containing this compound

Enantiomer of compound
None listed

Compound has enantiomers
None listed

Metabolite of compounds
None listed

Compound has metabolites

n-demethyldiltiazem

ID	Subject of Study	Study Name	Name	Type	Overall Effect	Enzymes	Transporters	Object	Object Metabolite	Precipitant
NPDI-yszOMw	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.	HLM-CBN	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP3A		diltiazem	n-demethyldiltiazem	cannabinol
NPDI-zkYApA	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.	HLM-CBD	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP3A		diltiazem	n-demethyldiltiazem	cannabidiol
NPDI-PS8_LQ	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.	HLM-THC	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP3A		diltiazem	n-demethyldiltiazem	delta-9-tetrahydrocannabinol
NPDI-ens_Gw	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.	CYP3A4-CBN	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP3A4		diltiazem	n-demethyldiltiazem	cannabinol
NPDI-FmAizA	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.	CYP3A4-CBD	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP3A4		diltiazem	n-demethyldiltiazem	cannabidiol
NPDI-8vislA	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.	CYP3A4-THC	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP3A4		diltiazem	n-demethyldiltiazem	delta-9-tetrahydrocannabinol

ID	Subject of Study	Name
NPDI-iHWMgQ	Cannabis (Cannabis sativa)	Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.

Compound information from external resources

Resource	Identifier
Google search	HSUGRBWQSSZJOP-RTWAWAEBSA-N