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11-hydroxy-delta-9-tetrahydrocannabinol
InChIKey: YCBKSSAWEUDACY-IAGOWNOFSA-N

11-OH-THC

Compound information managed by NaPDI


None listed

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-qk8qvw Cannabis (Cannabis sativa) Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids THC-OH-UGT1A9 In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT1A9
11-hydroxy-delta-9-tetrahydrocannabinol 11-nor-9-carboxy-delta9-tetrahydrocannabinol
NPDI-CWIhCg Cannabis (Cannabis sativa) Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids THC-OH-UGT1A10 In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT1A10
11-hydroxy-delta-9-tetrahydrocannabinol 11-nor-9-carboxy-delta9-tetrahydrocannabinol
NPDI-IQtjvw Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of delta-9-THC by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
delta-9-tetrahydrocannabinol 11-hydroxy-delta-9-tetrahydrocannabinol alpha-naphthoflavone
NPDI-qmmKqA Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Inhibition of 11-hydroxylation of delta-9-THC by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C
delta-9-tetrahydrocannabinol 11-hydroxy-delta-9-tetrahydrocannabinol sulfaphenazole
NPDI-abEayg Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of delta-9-THC by ketoconazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP3A
delta-9-tetrahydrocannabinol 11-hydroxy-delta-9-tetrahydrocannabinol ketoconazole

Compound information from external resources

Resource Identifier
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